Selected Publications

Marshall, K. M., W. L. Hurley, R. D. Shanks and M. B. Wheeler (2007). "Effects of suckling intensity on milk yield and piglet growth in lactation-enhanced alpha-lactalbumin transgenic gilts." Reproduction Fertility and Development 19(1): 318-319. 

Woodard, J. R., A. J. Hilldore, S. K. Lan, C. J. Park, A. W. Morgan, J. A. C. Eurell, S. G. Clark, M. B. Wheeler, R. D. Jamison and A. J. W. Johnson (2007). "The mechanical properties and osteoconductivity of hydroxyapatite bone scaffolds with multi-scale porosity." Biomaterials 28(1): 45-54.

Ford, J. A., S. G. Clark, E. M. Walters, M. B. Wheeler and W. L. Hurley (2006). "Estrogenic effects of genistein on reproductive tissues of ovariectomized gilts." Journal of Animal Science 84(4): 834-842.

Marshall, K. M., W. L. Hurley, R. D. Shanks and M. B. Wheeler (2006). "Effects of suckling intensity on milk yield and piglet growth from lactation-enhanced gilts." Journal of Animal Science 84(9): 2346-2351.

Wheeler, M. B., J. L. Rutledge, A. Fischer-Brown, T. VanEtten, S. Malusky and D. J. Beebe (2006). "Application of sexed semen technology to in vitro embryo production in cattle." Theriogenology 65(1): 219-227.

Clark, S. G., K. Haubert, D. J. Beebe, C. E. Ferguson and M. B. Wheeler (2005). "Reduction of polyspermic penetration using biomimetic microfluidic technology during in vitro fertilization." Lab on a Chip 5(11): 1229-1232.

Monaco, M. H., D. E. Gronlund, G. T. Bleck, W. L. Hurley, M. B. Wheeler and S. M. Donovan (2005). "Mammary specific transgenic over-expression of insulin-like growth factor-I (IGF-I) increases pig milk IGF-I and IGF binding proteins, with no effect on milk composition or yield." Transgenic Research 14(5): 761-773.

Reeder, A. L., M. O. Ruiz, A. Pessier, L. E. Brown, J. M. Levengood, C. A. Phillips, M. B. Wheeler, R. E. Warner and V. R. Beasley (2005). "Intersexuality and the cricket frog decline: Historic and geographic trends." Environmental Health Perspectives 113(3): 261-265.

Zeringue, H. C., M. B. Wheeler and D. J. Beebe (2005). "A microfluidic method for removal of the zona pellucida from mammalian embryos." Lab on a Chip 5(1): 108-110.

Fischer-Brown, A. E., B. R. Lindsey, F. A. Ireland, D. L. Northey, R. L. Monson, S. G. Clark, M. B. Wheeler, D. J. Kesler, S. J. Lane, K. A. Weigel and J. J. Rutledge (2004). "Embryonic disc development and subsequent viability of cattle embryos following culture in two media under two oxygen concentrations." Reproduction Fertility and Development 16(8): 787-793.

Malusky, S. A., P. H. Lopes, S. J. Kaufman and M. B. Wheeler (2004). "In vivo follicular response to gonadotropin stimulation and in vitro embryonic development following IVF in the Dmd/Mdx mutant mouse." Biology of Reproduction: 238-238.

Raty, S., E. M. Walters, J. Davis, H. Zeringue, D. J. Beebe, S. L. Rodriguez-Zas and M. B. Wheeler (2004). "Embryonic development in the mouse is enhanced via microchannel culture." Lab on a Chip 4(3): 186-190.

Wheeler, M. B., S. G. Clark and D. J. Beebe (2004). "Developments in in vitro technologies for swine embryo production." Reproduction Fertility and Development 16(1-2): 15-25.

Clark, S. G., E. M. Walters, D. J. Beebe and M. B. Wheeler (2003). "Determination of the BSA content needed for culture of porcine embryos fertilized in microchannels." Biology of Reproduction 68: 250-250.

Jackson, K. S., M. B. Wheeler and M. Fukuda (2003). "Trophinin: Expression and regulation in the porcine uterus." Biology of Reproduction 68: 157-158.

Marshall, K. M., R. D. Shanks and M. B. Wheeler (2003). "Increased nursing intensity stimulated greater lactational response in sows expressing a bovine alpha-lactalbumin transgene." Biology of Reproduction 68: 202-203.

Wheeler, M. B. (2003). "Production of transgenic livestock: Promise fulfilled." Journal of Animal Science 81: 32-37.

Wheeler, M. B., E. M. Walters and S. G. Clark (2003). "Transgenic animals in biomedicine and agriculture: outlook for the future." Animal Reproduction Science 79(3-4): 265-289.

Clark, S. G., E. M. Walters, D. J. Beebe and M. B. Wheeler (2002). "In vitro fertilization of porcine oocytes in polydimethylsiloxane (PDMS)-glass microchannels." Biology of Reproduction 66: 312-312.

Hassun, P., M. B. Wheeler, Silva, II, V. Freitas and I. T. N. Verreschi (2002). "Molecular screening of genes mapped in POF loci." Fertility and Sterility 78(3): S270-S270.

Hickman, D. L., D. J. Beebe, S. L. Rodriguez-Zas and M. B. Wheeler (2002). "Comparison of static and dynamic medium environments for culturing of pre-implantation mouse embryos." Comparative Medicine 52(2): 122-126.

Noble, M. S., S. Rodriguez-Zas, J. B. Cook, G. T. Bleck, W. L. Hurley and M. B. Wheeler (2002). "Lactational performance of first-parity transgenic gilts expressing bovine alpha-lactalbumin in their milk." Journal of Animal Science 80(4): 1090-1096.

Obrigado, M., M. B. Wheeler and L. Smith (2002). "Proceedings of the Annual Conference International Embryo Transfer Society - The Bourbon Hotel - Foz do Iguassu, Parana, Brazil January 12-15, 2001 - Preface and acknowledgments." Theriogenology 57(1).

Boston, W. S., G. T. Bleck, J. C. Conroy, M. B. Wheeler and D. J. Miller (2001). "Short communication: Effects of increased expression of alpha-lactalbumin in transgenic mice on milk yield and pup growth." Journal of Dairy Science 84(3): 620-622.

Glasgow, I. K., H. C. Zeringue, D. J. Beebe, S. J. Choi, J. T. Lyman, N. G. Chan and M. B. Wheeler (2001). "Handling individual mammalian embryos using microfluidics." Ieee Transactions on Biomedical Engineering 48(5): 570-578.

Monaco, M. H., J. B. Cook, K. A. Tappenden, M. B. Wheeler and S. M. Donovan (2001). "Intestinal lactase activity is increased in piglets suckling IGF-I transgenic sows." Faseb Journal 15(4): A644-A644.

Wheeler, M. B. and E. M. Walters (2001). "Transgenic technology and applications in swine." Theriogenology 56(8): 1345-1369.

Miller, K. D., G. T. Bleck, T. Wang, R. J. Feltes, L. B. Schook, F. K. McKeith, M. B. Wheeler and M. Ellis (2000). "Association of the porcine alpha-lactalbumin gene to growth, carcass, meat quality and reproductive traits." Journal of Applied Animal Research 17(1): 151-168.

Monaco, M. H., G. T. Bleck, J. B. Cook, M. B. Wheeler and S. M. Donovan (2000). "Transgenic overexpression of insulin-like growth factor-I in milk of swine using the bovine alpha-lactalbumin promoter and regulatory regions." Faseb Journal 14(4): A507-A507.

Nicastro, T. M. and M. B. Wheeler (2000). "Leukaemia Inhibitory Factor stimulates blastocyst development in vitro." Biology of Reproduction 62: 299-299.

Rahal, P., A. C. Latronico, M. B. F. Kohek, R. F. S. de Lucia, M. P. Milazzotto, M. B. Wheeler, J. B. S. Ferraz, J. P. Eler and J. F. Garcia (2000). "Polymorphisms in the bovine follicle-stimulating hormone receptor gene." Animal Genetics 31(4): 280-281.

White, B. R., R. W. Gerfen, E. M. Walters and M. B. Wheeler (2000). "Comparisons of culture of Chinese Meishan with Yorkshire pig embryos in vitro: Effects of protein supplementation and development." Journal of Applied Animal Research 17(1): 169-184.

Chan, N. G., J. T. Lyman, S. J. Choi, H. C. Zeringue, I. K. Glasgow, D. J. Beebe and M. B. Wheeler (1999). "Development of an embryo transport and analysis system: Material biocompatability." Theriogenology 51(1): 234-234.

Wilkie, P. J., A. A. Paszek, C. W. Beattie, L. J. Alexander, M. B. Wheeler and L. B. Schook (1999). "A genomic scan of porcine reproductive traits reveals possible quantitative trait loci (QTLs) for number of corpora lutea." Mammalian Genome 10(6): 573-578.

Bleck, G. T., B. R. White, D. J. Miller and M. B. Wheeler (1998). "Production of bovine alpha-lactalbumin in the milk of transgenic pigs." Journal of Animal Science 76(12): 3072-3078.

Choi, S. J., I. Glasgow, H. Zeringue, D. J. Beebe and M. B. Wheeler (1998). "Development of microelectromechanical systems to analyze individual mammalian embryos: Embryo biocompatability." Biology of Reproduction 58: 96-96.

Cotta, M. A., T. R. Whitehead and M. B. Wheeler (1998). "Identification of a novel adenylate cyclase in the ruminal anaerobe, Prevotella ruminicola D31d." Fems Microbiology Letters 164(2): 257-260.

Reeder, A. L., G. L. Foley, D. K. Nichols, L. G. Hansen, B. Wikoff, S. Faeh, J. Eisold, M. B. Wheeler, R. Warner, J. E. Murphy and V. R. Beasley (1998). "Forms and prevalence of intersexuality and effects of environmental contaminants on sexuality in cricket frogs (Acris crepitans)." Environmental Health Perspectives 106(5): 261-266.

Saif, L. J. and M. B. Wheeler (1998). "WAPping gastroenteritis with transgenic antibodies." Nature Biotechnology 16(4): 334-335.

Jeng, S. Y., G. T. Bleck, M. B. Wheeler and R. Jimenez-Flores (1997). "Characterization and partial purification of bovine alpha-lactalbumin and beta-casein produced in milk of transgenic mice." Journal of Dairy Science 80(12): 3167-3175.

Voelker, G. R., G. T. Bleck and M. B. Wheeler (1997). "Single-base polymorphisms within the 5' flanking region of the bovine alpha-lactalbumin gene." Journal of Dairy Science 80(1): 194-197.

White, B. R., J. Barnes, M. R. Cowan and M. B. Wheeler (1997). "Activation of in vivo matured porcine oocytes." Biology of Reproduction 56: 327-327.

Bleck, G. T., J. C. Conroy and M. B. Wheeler (1996). "Polymorphisms in the bovine beta-casein 5' flanking region." Journal of Dairy Science 79(3): 347-349.

Choi, B. K., G. T. Bleck, M. B. Wheeler and R. JimenezFlores (1996). "Genetic modification of bovine beta-casein and its expression in the milk of transgenic mice." Journal of Agricultural and Food Chemistry 44(3): 953-960.

Masters, W. G. and M. B. Wheeler (1996). "Timing of induced ovulation in C.B-17/Icr-scid/scid and B6SJLF(1) mice." Laboratory Animal Science 46(6): 663-666.

Tolbert, H. R., G. T. Bleck and M. B. Wheeler (1996). "Identification of differentially expressed transcripts during embryonic stem cell differentiation." Biology of Reproduction 54: 478-478.

Aktas, H., M. B. Wheeler, C. F. Rosenkrans, N. L. First and M. L. LeibfriedRutledge (1995). "Maintenance of bovine oocytes in prophase of meiosis I by high [cAMP](i)." Journal of Reproduction and Fertility 105(2): 227-235.

Aktas, H., M. B. Wheeler, N. L. First and M. L. LeibfriedRutledge (1995). "Maintenance of meiotic arrest by increasing [cAMP](i) may have physiological relevance in bovine oocytes." Journal of Reproduction and Fertility 105(2): 237-245.

Atac, E., R. Feltes, S. Conrad, J. Klaves, M. S. Rutherford, M. B. Wheeler and L. B. Schook (1995). "An Ecori Polymorphism at the Porcine Nebulin (Neb) Locus." Journal of Animal Science 73(3): 920-920.

Berger, T., E. Barnes and M. B. Wheeler (1995). "Sperm Plasma-Membrane (Pm) Proteins in Meishan (M) and European (E) Boars." Biology of Reproduction 52: 62-62.

Bleck, G. T., D. L. Johnsonroberts, R. Jimenezflores and M. B. Wheeler (1995). "DNA-Sequence of the Porcine Alpha-Lactalbumin 5' Flanking Region and Single-Base Polymorphisms within This Region." Animal Genetics 26(2): 101-103.

Boston, W. S., G. T. Bleck, M. B. Wheeler and D. J. Miller (1995). "Expression of Bovine Alpha-Lactalbumin in Transgenic Mice Increases Mammary Lactose Synthase Activity." Molecular Biology of the Cell 6: 2561-2561.

Davis, A. M., B. A. White and M. B. Wheeler (1995). "Rapid Communication - a Drai Restriction-Fragment-Length-Polymorphism at the Porcine 3-Hydroxy-3-Methylglutaryl-Coenzyme-a Reductase (Hmgcoar) Locus." Journal of Animal Science 73(1): 310-310.

Gerfen, R. W. and M. B. Wheeler (1995). "Isolation of embryonic cell-lines from porcine blastocysts." Animal Biotechnology 6(1): 1-14.

Jarrell, V. L., H. A. Lewin, Y. Da and M. B. Wheeler (1995). "Gene-Centromere Mapping of Bovine Dya, Drb3, and Prl Using Secondary Oocytes and First Polar Bodies - Evidence for 4-Strand Double Crossovers between Dya and Drb3." Genomics 27(1): 33-39.

Wheeler, M. B., L. A. Rund, G. T. Bleck, M. M. Izard, L. R. Grum, A. M. Davis, E. D. Hunt, B. R. White and J. E. Barnes (1995). "Production of Chimeric Swine from Embryonic Stem (Es) Cells." Biology of Reproduction 52: 136-136.

Wheeler, M. B., J. A. Noble and V. L. Jarrell (1995). "Production of Live Offspring with Predicted Genotypes Using Pcr-Rflp Analysis of Polar Bodies from Mouse Oocytes." Molecular Reproduction and Development 40(3): 267-272.

White, B. R. and M. B. Wheeler (1995). "Examination of Ovulation Rate, Uterine and Fetal Interactions, and Reproductive Age in Chinese-Meishan, Yorkshire, and Reciprocal Cross Gilts - Effects of Fetal and Maternal Genotypes." Animal Reproduction Science 39(2): 147-158.

White, B. R., Y. H. Lan, F. K. McKeith, J. Novakofski, M. B. Wheeler and D. G. McLaren (1995). "Growth and Body-Composition of Meishan and Yorkshire Barrows and Gilts." Journal of Animal Science 73(3): 738-749.

Cotta, M. A., M. B. Wheeler and T. R. Whitehead (1994). "Cyclic-Amp in Ruminal and Other Anaerobic-Bacteria." Fems Microbiology Letters 124(3): 355-359.

Davis, A. M., B. A. White and M. B. Wheeler (1994). "Rapid Communication - a Taqi Restriction-Fragment-Length-Polymorphism at the Porcine Cholesterol 7-Alpha-Hydroxylase (Cyp7) Locus." Journal of Animal Science 72(3): 797-797.

Foley, G. L., L. A. Rund and M. B. Wheeler (1994). "Factors Affecting Murine Embryonic Stem-Cell Teratoma Development." Biology of Reproduction 50: 127-127.

Gerfen, R. W., B. R. White, M. A. Cotta and M. B. Wheeler (1994). "Comparison of the Semen Characteristics of Fengjing, Meishan and Yorkshire Boars." Theriogenology 41(2): 461-469.

Rund, L. A., L. R. Grum, G. T. Bleck, T. E. Leach and M. B. Wheeler (1994). "Comparison of Murine Es-Cell and Porcine Es-Like Cell Sensitivity to Antibiotic-G418." Biology of Reproduction 50: 125-125.

Wheeler, M. B. (1994). "Development and Validation of Swine Embryonic Stem-Cells - a Review." Reproduction Fertility and Development 6(5): 563-568.

Allen, M. R. and M. B. Wheeler (1993). "An Rsa I Rflp at the Porcine Protein-Kinase-C Epsilon Polypeptide (Prkce) Locus." Animal Genetics 24(4): 330-330.

Davis, A. M., B. A. White and M. B. Wheeler (1993). "A Taqi Rflp at the Porcine Low-Density-Lipoprotein Receptor (Ldlr) Locus." Animal Genetics 24(4): 330-330.

Shalhevet, D., R. J. Feltes, E. T. Atac, J. Klaves, S. Conrad, M. P. Murtaugh, M. B. Wheeler and L. B. Schook (1993). "Rapid Communication - a Mspl Polymorphism at the Porcine Interleukin-6 (Il-6) Locus." Journal of Animal Science 71(12): 3478-3478.

Wheeler, M. B. and D. R. Campion (1993). "Animal Production - a Longstanding Biotechnological Success." American Journal of Clinical Nutrition 58(2): S276-S281.

White, B. R., D. G. McLaren, P. J. Dziuk and M. B. Wheeler (1993). "Age at Puberty, Ovulation Rate, Uterine Length, Prenatal Survival and Litter Size in Chinese Meishan and Yorkshire Females." Theriogenology 40(1): 85-97.

White, B. R., Y. H. Lan, F. K. McKeith, D. G. McLaren, J. Novakofski, M. B. Wheeler and T. R. Kasser (1993). "Effects of Porcine Somatotropin on Growth and Carcass Composition of Meishan and Yorkshire Barrows." Journal of Animal Science 71(12): 3226-3238.

Slenning, B. D. and M. B. Wheeler (1989). "Risk-Evaluation for Bovine Embryo Transfer Services Using Computer-Simulation and Economic Decision-Theory." Theriogenology 31(3): 653-673.

Wheeler, M. B. and G. E. Seidel (1989). "Capacitation of Bovine Spermatozoa by Lysophospholipids and Trypsin." Gamete Research 22(2): 193-204.

Wheeler, M. B. and J. D. Veldhuis (1989). "Facilitative Actions of the Protein Kinase-C Effector System on Hormonally Stimulated Adenosine-3',5'-Monophosphate Production by Swine Luteal Cells." Endocrinology 125(5): 2414-2420.

Wheeler, M. B. and J. D. Veldhuis (1989). "Purification of 3 Forms of Chromatographically Distinct Protein Kinase-C from the Swine Ovary." Molecular and Cellular Endocrinology 61(1): 117-122.

Slenning, B. D. and M. B. Wheeler (1988). "Risk-Evaluation for Decision-Making in Embryo Transfer." Theriogenology 29(1): 309-309.

Wheeler, M. B. and G. E. Seidel (1988). "Capacitation of Bull Sperm by Lysophospholipids and Trypsin." Theriogenology 29(1): 325-325.

Wheeler, M. B. and J. D. Veldhuis (1988). "Interactions of Protein Kinase-C with Receptor-Mediated and Non-Receptor-Mediated Cyclic-Amp Generation in Swine Granulosa-Cells." Molecular and Cellular Endocrinology 59(3): 195-203.

Wheeler, M. B. and J. D. Veldhuis (1987). "Catalytic and Receptor-Binding Properties of the Calcium-Sensitive Phospholipid-Dependent Protein-Kinase (Protein-Kinase-C) in Swine Luteal Cytosol." Molecular and Cellular Endocrinology 50(1-2): 123-129.

Wheeler, M. B. and G. E. Seidel (1987). "Zona-Pellucida Penetration Assay for Capacitation of Bovine Sperm." Gamete Research 18(3): 237-250.

Wheeler, M. B. and G. E. Seidel (1986). "Time Course of Invitro Capacitation of Frozen and Unfrozen Bovine Spermatozoa." Theriogenology 25(1): 216-216.

Wheeler, M. B., G. B. Anderson, R. H. Bondurant and G. H. Stabenfeldt (1982). "Postpartum Ovarian-Function and Fertility in Beef-Cattle That Produce Twins." Journal of Animal Science 54(3): 589-593.

Wheeler, M. B., G. B. Anderson, C. J. Munro and G. H. Stabenfeldt (1982). "Prolactin Response in Beef-Cows and Heifers Suckling One or 2 Calves." Journal of Reproduction and Fertility 64(1): 243-249.

Wheeler, M. B., J. W. Scheer, G. B. Anderson and R. H. Bondurant (1979). "Postpartum Fertility in Beef-Cattle Producing Twins." Theriogenology 12(6): 383-387.

Last updated April 1, 2007